You can become a Vampire by means; you can be bitten by a Vampire during normal play, you or can accept "the Gift" from Lord Harkon or another Vampire of Castle Volkihar. When you are a Vampire, if you do not feed, you become hated by people and become weak to fire and the sun over time. But as a Vampire, you some pretty cool powers.
But if you want to cure Vampirism, first you need to go to The Death Man's Drink, in Falkreath.
Then talk to Valga Vinica, the barmaid. Ask her about rumors; she will to mention Falion of Morthal.
This will start the quest "Rising at Dawn". He will ask you to bring him a filled Black Soul Gem, Black Soul Gems can be found throughout Skyrim, or you can buy one of him. You will a Soul Gem by two ways; killing an enemy with a weapon with an Soul Trapping Enchantment or by hitting an enemy with the Magic Spell - Soul Trap and then killing them.
I found the easiest way is to hit them with Soul Trap and then kill them because I didn't have a Soul Trapping Enchanted Weapon on me. You can by the Spell Tome: Soul Trap book off of Dragonsreach Court Wizard Farengar Secret-Fire, in Whiterun. Then I found a bandit, used Soul Trap on them and killed them, doing this filled my Black Soul Gem.
Once you have a Filled Black Soul Gem, return to Falion and he will tell you to wait for him at Dawn at a location, just north of Mortal. Falion will begin the ritual, your vision will go dark, then blighty white, then you are cured of Vampirism.
If you catch Vampirism again, the quest can be repeated to cure Vampirism again.
On the other hand, you can talk to Aela, one of the Companions. Where you have the ability to turn into a Werewolf, which will cure you of Vampirism as well.
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